Makes eating a pleasurable, nourishing experience – with DPP-IV enzymes and much more

Same great product as GutZyme® Assist – new name!

DPP-IV enzymes offer a whole new promise of ease when it comes to digesting casein and gluten. GutZyme® by Organic 3, Inc. offers these revolutionary enzymes as part of a comprehensive digestive enzyme supplement. So your clients can relax – not worry – when eating a meal.

This custom formulation is also especially helpful for people transitioning to a diet with more healthy fats, as it has three types of lipase that help digest fat. And GutZyme® includes enzymes to help digest complex carbs in gassy foods like beans, cabbage and broccoli – and starchy foods like oats and rice.

Our customers love to have GutZyme® on hand when they’re traveling, attending parties, or in environments where they don’t have control of the ingredients in the food.



  • Provides comprehensive enzyme support for comfortable digestion absorption of nutrients.*
  • Gives you the enzymes that support in the digestion of carbs, vegetables, protein, fats and sugars: Amylase, glucoamylase, invertase, lactase, maltase, alpha-galactosidase, beta-glucanase, phytase, lipase, and protease peptidase complex.*
  • Gives you three different types of lipase, providing 500 FIP (Fungal Lipase International Standard, or 1 unit of enzyme activity) for help digesting fats.
  • Contains DPP-IV enzymes that may support the digestion of casein and gluten.*
  • Is encapsulated in a cellulose, vegetarian capsule.
  • Is safe to open and ingest without encapsulation.
  • Is free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten, yeast and soybeans.
  • Does not contain artificial colors, flavors or preservatives.
  • Does not contain HCL (hydrochloric acid) or pepsin.
  • Can be used sequentially or in tandem with GutZyme® HCl. Some customers start with GutZyme® HCl and then move onto only GuZyme® after their stomach is functioning well. Some use the two in tandem for different meals over the same day.

Warning: GutZyme® is not recommended for children under the age of 3, unless otherwise prescribed by a physician. For toddlers and sensitive adults, a smaller dose may be obtained by pulling apart the capsule, taking a small portion of the contents and mixing with food.


Makes eating a pleasure again!

Food is meant to be nourishing and pleasurable – not a minefield! As you help your clients recover the joy of eating, digestive enzymes can be a powerful tool. GutZyme® gives you a complete mix of digestive enzymes that support the breakdown of carbs, vegetables, protein, fats and sugars.

It’s a powerful form of support for the digestive tract; and the perfect complement to our wildly popular GutZyme® HCl supplement.

To be clear, unlike GutZyme® HCl, GutZyme® does not contain hydrochloric acid (HCL) or pepsin. GutZyme® is a supplement for people who already make enough HCL in their stomachs.

GutZyme® focuses on digestive enzymes alone. And while it has lipase, lactase, phytase and the protease complex found in GutZyme® HCl, it also includes some other more targeted enzymes:

For carbs, you get:

  • Amylase, which is typically found in your saliva, the first step in digesting starch.
  • Glucoamylase, which breaks down starch found in most vegetables.

For sugars, in addition to lactase that helps with dairy, you get:

  • Invertase, which splits common table sugars into fructose and glucose.
  • Maltase, which breaks down maltose. Maltose develops in many starchy vegetables like sweet potatoes, nuts and legumes when they’re digested or cooked.

When it comes to vegetables, GutZyme® gives you:

  • Alpha-galactosidase is clinically shown to help reduce gassiness.* How? It seems to break down the sugar-fat complexes commonly found in hard-to-digest foods like broccoli, cabbage, peanuts and beans.
  • Beta-glucanase helps you break down the beta glucans found in heavy grains like oats, barley and rye as well in fungi like Candida.
  • Phytase – most plant-based foods contain phytate or phytic acid. Phytic acid can make it difficult for the body to absorb certain nutrients. Phytase cleaves phosphorus off of the phytic acid, liberating the phosphorus as well as other minerals like magnesium, iron, calcium and zinc, making these available to your body.

GuZyme® gives you all these carefully selected enzymes so your body can maximize the nourishment from a real food diet.*

But these aren’t the only targeted enzymes GutZyme® gives you….


DPP-IV enzymes help with casein and gluten

The discovery of DPP-IV enzymes opened up a whole new world of potential support for people who have trouble with certain proteins like gluten and casein.*

This special enzyme is one of the few enzymes that can help with the breakdown of proteins like gluten and casein, rich in the amino acid, proline.*

DPP-IV has been shown to help the breakdown of gluten in lab studies.* Clinical research on DPP-IV is limited. However, one small trial found that supplementing with a multi-enzyme mix that contained DPP-IV enzymes supported comfortable digestion, as well as cognitive and social health.*  

Most health experts recommend using it as a safeguard if you’re worried something may contain gluten or casein.* Please understand this doesn’t mean digging into a loaf of bread or bowl of pasta simply because you’ve added this to your clients’ list of supplements.

The DPP-IV enzymes in GutZyme® serve more as an additional safety net than as something that can reverse the gluten or dairy challenge you’re facing.

Finally, as an added bonus, DPP-IV enzymes also seem to help support a strong immune response.* And certainly, that highlights the other advantage of boosting your digestive enzymes…


Digestive enzymes aren’t just for digestion

While digestive enzymes play an important role in healthy digestion, growing evidence indicates the benefits are far greater…*

  • In one double-blind placebo-controlled trial involving 101 children, ages 3-9, half the participants took digestive enzyme supplements for three months. At the end of the trial, the children who took the digestive enzymes exhibited a consistently noticeable improvement in their emotional health and overall behavior as well as improvements in digestion.

Given the role your gut plays in the health of your brain, it’s no surprise that a number of studies are showing that digestive enzymes can help your emotional and cognitive health as well.*

  • Over a dozen clinical studies show protease enzymes may fight inflammation and help with joint mobility.* Using enzymes for occasional pain has been linked to not only effective pain relief, but also shorter recovery time.* Professional skiers and hockey players alike have relied on enzymes to help them stay in the sport, despite the bumps and bruises they receive while competing.*


“Like magic!”

“Will order more. GutZyme® works like magic and it’s so easy to take!” – Judy M.

When digestion is off, it can make life miserable. Poor digestion brings gas, bloating, stomach cramps and other discomforts on its own. Even worse, poor digestion can rob your clients of the nutrients needed to feel energized and function at their best.

It’s a double whammy!

Digestion is also a complex process. Fixing digestion isn’t a one-size-fits-all solution.

As one of our customers exclaimed, the difference GutZyme® made in how she felt was “like magic!”

Of course, GutZyme® can’t work miracles in a vacuum. It can’t make up for a stressful lifestyle or a diet of donuts and soda. But if you’re working hard to bring your clients’ diet and health back into balance, the digestive enzymes in GutZyme® may be the lynchpin you’ve been seeking.



Take 2 capsules with each meal, or as guided by a healthcare professional. For children and sensitive adults, a smaller dose may be obtained by pulling apart the capsule and taking a portion of the contents.

Important: The supplements we carry are premium, pure and potent. Therefore, it’s critically important to start slowly, with a lower dosage than recommended. For example, a very small dose every other day, or even once a week, until you can determine how the supplement affects your body and what dose feels right for you. 



Store in a cool, dry area, away from direct light.


Ready to see if GutZyme® can make the difference for your clients?

If you’re a retailer, here’s more information on where to buy GutZyme®.

You can also apply for a wholesale account today (practitioners and retailers alike)!



*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


[1] Lambeir AM et al. Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV. Critical Reviews In Clinical Laboratory Sciences: 40(3), 2003
[2] DPP-IV Enzymes: Clearing Up The Confusion About Activity Units. Prothera and Klaire Labs Newsletter. Summer 2010. Viewed 4/4/17 at
[3] Prothera and Klaire Labs Newsletter.
[4] Lambeir AM et al. Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV. Critical Reviews In Clinical Laboratory Sciences: 40(3), 2003
[5] Ganiats TG et al. Does Beano prevent gas? A double-blind crossover study of oral alpha-galactosidase to treat dietary oligosaccharide intolerance. J Fam Pract. 1994 Nov;39(5):441-5.
[6] Saad K et al. A Randomized, Placebo-controlled Trial of Digestive Enzymes in Children with Autism Spectrum Disorders. Clinical Psychopharmacology and Neuroscience. 2015;13(2):188-193.
[7] Chintalacharuvu SR et al. Treatment of collagen induced arthritis by proteolytic enzymes: immunomodulatory and disease modifying effects. J Rheumatol. 2001 Sep;28(9):2049-59.
[8] Leonard L. Systemic Proteolytic Multi-Enzyme Therapy. Nutrition Review. May 16, 2014. Viewed 4/17 at
[9] Leonard L. 2014.